The Regional Research Station, Faridkot, established in April 1970, has about 55 acre of rich fertile, leveled and well laid out farm area for experimentation. Historically, the campus of this station is located at the same place where "DAVIS MODEL AGRICULTURE FARM AND FARMER'S HOUSE" was established in 1910 for the welfare of Farmers of Princely State of Faridkot, testified by the entrance gate of the station. It is located in the agriculturally most potential region - Zone IV (South- Western Zone) of Punjab. The Zone IV lies between the central Plain Zone on the North - East and Western Zone on the South - West. The Zone IV comprises 21 development blocks: Bhikhwind, Patti and Valtoha of Ameritsar district; Zira, Ghall Khurd and Ferozpur of Ferozpur district; Moga-I, Moga-II, Nihalsingh Wala and Bagha Purana of Moga district; Phul, Rampura and Talwandi Sabo of Bhatinda district; Mansa and Budhlada of Mansa district; and Sehna, Barnala, Sangrur, Sunam and Lehragaga of Sangrur district. It covers about 10,049 km² (14,91,300 ha, gross cropped area) area, representing nearly 20 per cent area of the state.

The altitude of the zone varies between 200 to 300 m above mean sea level. The soil are largely of alluvial origin and coarse to fine in texture. Mostly the soils are alkaline in reaction having pH more than 7.5. The water table in the region varies from 2 m to 10m below the ground level. The sub-soil water is brackish and salty, which is not fit for irrigation to crops. The average annual rainfall and potential evapo-transpiration of the zone is 419 mm and 1424 mm, respectively. The principal Kharif crops of the zone are rice, cotton, sugarcane and mung bean. The important Rabi crops are wheat, chickpea, rapeseed and mustard. In addition, horticulture and vegetable crops also cover a considerable area in this zone.

The research on cotton has since been strengthened and accelerated under the All India Coordinated Research on Cotton sponsored and sanctioned by the ICAR in 1967. The erstwhile PAU catered to the requirements of both Punjab and Haryana at that time. Initially, there was one main center at Hisar and a sub-centre at Ludhiana under the project. The HAU came into existence in December, 1970 and PAU was thus left with only one sub-centre at Ludhiana. However, in April 1972 the Ludhiana sub-centre was upgraded into main center with a sub-centre at Faridkot, later in 2000 Faridkot was designated as the main center and in 2011 the sub-centre from Ludhiana was shifited to Bathinda.

Realizing the importance of sugarcane crop in the State, Indian Council of Agricultural Research sanctioned All India Co-ordinated Research Project on Sugarcane at Regional Research Station, Faridkot during 1995. Faridkot Station was working as coordinating Centre for conducting Zonal trials in breeding and agronomy disciplines in North West Zone. In 2021 the coordinating centre was shifited to Gurdaspur, however sugarcane research on priority areas such as water and nutrient use efficiency are still being carried out at this station. In addition to cotton and sugarcane, multi location testing on bajra, chickpea, mungbean, arhar, lentil, sunflower and mustard crops is also conducted at this station.

Research on high income horticultural crops, avocado, almond, dragon fruit and strawberry is initiated during 2022.